Back to MPLN Home Client Services: +1 865.380.9746

Chromosome Analysis Bone Marrow

Test ID: CYTO BM CPT Code: By report 88237, 88264, 88291
Expected Turnaround Time
7 days
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Clinical Information
Chromosome analysis on samples suspected of harboring a hematologic disorder. Bone marrow is the preferred sample type in most hematologic conditions because it more accurately reflects what occurs in vivo.
Requisition Forms
Oncology Pathology Requisition

Specimen Requirements

Specimen Requirements

•Bone Marrow Aspirate: 5 mL, NaHep preferred (EDTA accepted)

•Bone Marrow Core: 5mm in ≥ 4 mL tissue culture, transport media (RPMI using 10 mL sterile transport tube  

Specimen Stability

•Bone Marrow Aspirate: 72 hours

•Bone Marrow Core: 72 hours

Storage Requirements

•Bone Marrow Aspirate: 2°C to 25°C

•Bone Marrow Core: 15°C to 25°C

•Fixed Cytogenetically Prepared Cells: -28°C to -15°C

Shipping Recommendations

AMBIENT, Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures. Separate gel pack from specimen. Do not freeze.

 

Specimen Rejection Criteria

Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells

Test Details

Synonyms

Chromosome analysis, cytogenetic analysis, karyotyping, G-banding

Keywords
Cytogenetics, Leukemia, Oncology, Oncology Cytogenetics, Karyotyping
Test Method
Karyotyping
Methodology Category
Cytogenetics
Regulatory Status
RUO
Special Considerations

All attempts will be made to process and report samples received > 72 hours post-collection.  Bone marrow is the sample of choice in most heme malignancies.

Associations

Hematological malignancies