Trisomy 21*
Expected Turnaround Time
9 days
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Clinical Information
An extra copy of chromosome 21 is the cause of Down syndrome. An increased risk is seen with the increase in maternal age. *Testing performed by affiliate laboratory.
Specimen Requirements
Specimen Requirements
Whole Blood: 5 mL, EDTA preferred (NaHep accepted)
Specimen Stability
72 hours
Storage Requirements
Whole Blood: 2°C to 25°C
Shipping Conditions
Ambient, Refrigerated
Shipping Recommendations
AMBIENT, Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures. Separate gel pack from specimen. Do not freeze.
Specimen Rejection Criteria
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells
Test Details
Synonyms
+21, CEP 21, trisomy-21
Keywords
Fluorescence in-situ Hybridization, Prenatal Diagnostics, Women's Health, Constitutional FISH
Test Method
Fluorescence in situ hybridization (FISH)
Methodology Category
FISH
Special Considerations
All attempts will be made to process and report samples received > 72 hours post-collection.
Associations
Down syndrome