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Leukemia/Non-Hodgkin Lymphoma

Test ID: FLOW CPT Code: 88184, 88185xn, and 88187 or 88188 or 88189
Expected Turnaround Time
1 day
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Clinical Information
Immunophenotyping, myeloid / lymphoid markers for hematological malignancies. Flow panels include B cell (Kappa, Lambda, CD10, CD19, CD20, CD38, CD45, CD5); TNK (CD57, CD38, CD8, CD7, CD4, CD3, CD45, CD2, CD56); Myeloid (CD11b, CD34, HLA-DR, CD13, CD19, CD14, CD16, CD45, CD33, CD117 with add-ons as needed); Plasma Cells (icKappa, icLambda, CD56, CD19, CD38, CD45, CD138, CD117); CLL (FMC7, CD49d, CD200, CD19, CD23, CD45, CD5); Blasts (icTdT, icMPO, CD64, CD10, CD19, icCD3, icCD79a, CD34, CD45).
Requisition Forms
Oncology Pathology Requisition

Specimen Requirements

Specimen Requirements
  • Whole Blood: 4 mL (minimum of 0.5 mL with 107 cells), NaHep preferred (EDTA accepted)
  • Bone Marrow Aspirate: 2 mL (minimum of 0.5 mL with 107 cells), NaHep preferred (EDTA accepted)
  • Bone Marrow Core Biopsy: 2 cm (minimum of 1 cm), Sterile container with 2-4 mL RPMI transport media or sterile saline
  • Fresh Tissue: 5 mm3, Sterile container with 2-4 mL RPMI transport media or sterile saline
  • Fine Needle Aspirate (FNA): 4 mL (minimum of 0.5 mL with 107 cells), Sterile container with 2-4 mL RPMI transport media or sterile saline
  • Fluids: CSF, pleural, synovial, pericardial fluids, BAL: 4 mL (minimum of 0.5 mL with 107 cells), Sterile container with 2-4 mL RPMI transport media or sterile saline
Specimen Stability

Specimen stable for 48 hours at 4°C.

Storage Requirements

2°C to 8°C

Shipping Conditions
Refrigerated
Shipping Recommendations

REFRIGERATED, Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures. Separate gel pack from specimen

Specimen Rejection Criteria

Specimens stored at incorrect temperature; Non-viable specimens; Specimens in inappropriate anticoagulant; Too few cells; Hemolysis; Specimen clotted

Test Details

Synonyms

Immunophenotyping, myeloid / lymphoid markers

Keywords
Pathology, Flow Cytometry, Leukemia, Oncology, Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Chronic Myelogenous Leukemia (CML), Hypereosinophilia / Mast Cell, Chronic Lymphocytic Leukemia (CLL), Lymphoma, Myelodysplastic Syndrome (MDS), Myelopro, flow, leukemia, immunophenotyping, myeloid, lymphoid, non-Hodgkin lymphoma, cytometry
Test Method
Flow cytometry
Methodology Category
Flow Cytometry
Regulatory Status
ASR
Associations

Acute myeloid leukemia, Acute lymphoblastic leukemia, Chronic lymphocytic leukemia, Non-Hodgkin lymphoma