CD79a, technical only

Test ID: I CD79a TC CPT Code: 88342-TC

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Expected Turnaround Time

2 days
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.

Clinical Information

CD79a is a pan B-cell marker that first appears during the pre-B-cell stage, early in maturation, and persists until the plasma cell stage where it's found intracellularly. CD79a is useful as a marker in antibody panels to differentiate classic Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma and aggressive B-cell lymphomas that may show Hodgkin-like features. Technical component only. Pathologist read not included.

Requisition Forms

Immunohistochemistry Requisition

Specimen Requirements

Fresh Tissues: Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED)
Formalin-fixed Paraffin Embedded Tissue (FFPE blocks): FFPE Block, Formalin Fixed
Unstained slides: 2 slides (3-5 μM) per stain (min 1 slide per stain), Formalin Fixed

Specimen Stability

Fresh Tissue Tissues: ≤ 72 Hours
Formalin-fixed Paraffin Embedded Tissue (FFPE blocks): Indefinite
Unstained slides: Indefinite
Stained slides: Indefinite

Storage Requirements

15°C to 25°C

Shipping Conditions

Ambient

Shipping Recommendations

Fresh Tissues: AMBIENT
Formalin-fixed Paraffin Embedded Tissue (FFPE blocks) and unstained slides: AMBIENT, Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures. Separate gel pack from specimen.
Specimens may be transferred to 70% alcohol for transportation purposes after fixation in 10% NBF or B plus.

Specimen Rejection Criteria

Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.

Test Details

Synonyms

B-cell antigen receptor complex-associated protein alpha chain, Ig-Alpha, IgA, MB1, MB-1, Membrane-Bound Immunoglobulin-Associated Protein, MB-1 Membrane Glycoprotein, Immunoglobulin-Associated Alpha

Test Method

Immunohistochemistry

Methodology Category

IHC

Regulatory Status

IVD, CE-marked

Special Considerations

Fresh Tissues: Specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Samples must be tested 3 months after placing in ethanol.
Unstained slides: Positively charged glass slides required to prevent background staining and prevent tissue loss. Slides should be left unbaked.

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