Back to MPLN Home Client Services: +1 865.380.9746

Ki67, technical only

Test ID: I KI67 TC CPT Code: 88360-TC
Expected Turnaround Time
2 days
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Clinical Information
Ki-67 is a nuclear protein associated with cellular proliferation. In pathology, Ki-67 is widely used to assess the proliferation rate of tumor cells, which can be an important indicator of tumor aggressiveness and prognosis. High Ki-67 expression is often correlated with more aggressive cancers, and its evaluation can guide treatment decisions, particularly in assessing the need for chemotherapy. Technical component only. Pathologist read not included.
Requisition Forms
Immunohistochemistry Requisition

A series of immunohistochemistry (IHC) tests used for detai…

View Details Download
Oncology Pathology Requisition

A set of pathology tests designed for cancer diagnostics, i…

View Details Download

Specimen Requirements

Specimen Requirements
  • Fresh Tissues: Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED)
  • Formalin-fixed Paraffin Embedded Tissue (FFPE blocks): FFPE Block, Formalin Fixed
  • Unstained slides: 2 slides (3-5 μM) per stain (min 1 slide per stain), Formalin Fixed
Specimen Stability
  • Fresh Tissue Tissues: ≤ 72 Hours
  • Formalin-fixed Paraffin Embedded Tissue (FFPE blocks): Indefinite
  • Unstained slides: Indefinite
Storage Requirements

15°C to 25°C

Shipping Conditions
Ambient
Shipping Recommendations
  • Fresh Tissues: AMBIENT
  • Formalin-fixed Paraffin Embedded Tissue (FFPE blocks) and unstained slides: AMBIENT, Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures. Separate gel pack from specimen.
  • Specimens may be transferred to 70% alcohol for transportation purposes after fixation in 10% NBF or B plus.
Specimen Rejection Criteria

Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected. 

Test Details

Synonyms

Antigen Kiel 67, Marker of proliferation Kiel 67, MKI67, Ki-67, PPP1R105l, MIB-, MIB-1, Molecular Immunology Borstel Antibody 1

Test Method
Immunohistochemistry
Methodology Category
IHC
Regulatory Status
IVD, CE-marked
Special Considerations
  • Fresh Tissues: Specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Samples must be tested 3 months after placing in ethanol.
  • Unstained slides: Positively charged glass slides required to prevent background staining and prevent tissue loss. Slides should be left unbaked.