Chromosome Analysis Peripheral Blood (Constitutional)
Expected Turnaround Time
7 days
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Clinical Information
Constitutional cytogenetic analysis of peripheral blood lymphocytes. This is performed to detect germline chromosomal abnormalities, including numerical and structural abnormalities.
Specimen Requirements
Specimen Requirements
Whole Blood: 5 mL, EDTA preferred (NaHep accepted)
Specimen Stability
72 Hours
Storage Requirements
Whole Blood: 2°C to 25°C
Fixed Cytogenetically Prepared Cells: -28°C to -15°C
Shipping Recommendations
AMBIENT, Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures. Separate gel pack from specimen. Do not freeze.
Specimen Rejection Criteria
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells
Test Details
Synonyms
Chromosome analysis, cytogenetic analysis, karyotyping, G-banding
Keywords
Cytogenetics, Prenatal Diagnostics, Women's Health, Constitutional Cytogenetics, Karyotyping
Test Method
Karyotyping
Methodology Category
Cytogenetics
Regulatory Status
RUO
Special Considerations
All attempts will be made to process and report samples received > 72 hours post-collection. Bone marrow is the sample of choice in most heme malignancies.
Associations
Numerical and structural chromosomal abnormalities associated with constitutional disease