1p/19q Co-deletion (Oligodendroglioma)*, paraffin
Expected Turnaround Time
9 days
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Clinical Information
FISH testing on paraffin-embedded cells for detection of deletions of chromosome arms 1p and 19q. These deletions are frequent genetic abnormalities in primary human gliomas and are especially common in oligodendrogliomas. *Testing performed by affiliate laboratory.
Specimen Requirements
Specimen Requirements
- FFPE Tissue Block
- Unstained FFPE tissue: 5 slides preferred (3 slides minimum) cut at 3-5 μM and mounted on positively charged slides.
Specimen Stability
Stable indefinitely
Storage Requirements
15°C to 25°C
Shipping Conditions
Ambient
Shipping Recommendations
AMBIENT, Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures. Separate gel pack from specimen. Do not freeze.
Specimen Rejection Criteria
Improper fixative; Tissue not fixed; Insufficient tissue; Specimen exposed to extreme temperature
Test Details
Synonyms
1p-/19q-, 1p36-/19q13-, del(1)(p36), del(19)(q13)
Keywords
Fluorescence in-situ Hybridization, Oncology, Oncology FISH Probes, Neural
Test Method
Fluorescence in situ hybridization (FISH)
Methodology Category
FISH
Special Considerations
Tissues should be fixed in 10% neutral buffered formalin (NBF). Tissues preserved in B+ fixative or decalcified are usually not suitable for FISH. Assay requires 3 unstained slides minimum (two for each probe) and one H&E stained slide. If unstained slides are sent, cut FFPE tissue sections at 3-5 μm thickness, mounted on positively charged slides.
Associations
Oligodendroglioma