Back to MPLN Home Client Services: +1 865.380.9746

SRY/CEP X*

Test ID: F SRY* CPT Code: 88377 OR 88275 x2, 88271 x2, 88291 x1

Expected Turnaround Time
9 days
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.

Clinical Information
FISH test on hematologic specimens for detection of del Yp11.3. This test is useful in biological sex determination in constitutional studies or to determine chimerism in cases of opposite sex bone marrow / stem cell transplants. *Testing performed by affiliate laboratory.

Specimen Requirements


Specimen Requirements
  • Whole Blood: 5 mL, EDTA preferred (NaHep accepted)
  • Bone Marrow Aspirate: 3 mL, EDTA preferred (NaHep accepted)

Specimen Stability

72 hours


Storage Requirements
  • Whole Blood: 2°C to 25°C
  • Bone Marrow Aspirate: 2°C to 25°C
  • Fixed Cytogenetically Prepared Cells: -28°C to -15°C

Shipping Conditions
Ambient, Refrigerated

Shipping Recommendations

AMBIENT, Use a refrigerated (NOT FROZEN) gel pack in the shipment to protect from extreme temperatures. Separate gel pack from specimen. Do not freeze.


Specimen Rejection Criteria

Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells


Test Details


Synonyms

SRY region, Yp11.3/Xp11.1q11.1


Keywords
Fluorescence in-situ Hybridization, Transplantation

Test Method
Fluorescence in situ hybridization (FISH)

Methodology Category
FISH

Special Considerations

All attempts will be made to process and report samples received > 72 hours post-collection.  Bone marrow is the sample of choice in most heme malignancies.


Associations

Bone marrow, stem cell transplant